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Dermatite allergica da contatto

Che cos’è la dermatite allergica da contatto?

La dermatite allergica da contatto è una comune affezione cutanea caratterizzata dalla presenza di lesioni eritemato maculo- vescicolo- crostose e da prurito, causati dal contatto con un allergene. Il processo immunologico alla base della dermatite allergica da contatto è una reazione di ipersensibilità ritardata e le sostanze di questa risposta sono numerosissime. Vista la prevalenza di molecole utilizzate in diverse attività professionali, la dermatite allergica da contatto si presenta talora come una malattia professionale che può colpire diverse categorie di lavoratori quali parrucchieri, muratori, lavoratori dell’industria farmaceutica e cosmetica ecc..

Quali sono le cause della dermatite allergica da contatto?

L’allergia ai metalli, e in particolare al nichel,  rappresenta la causa più comune di dermatite allergica da contatto. I metalli(nichel,cromo,cobalto) non sono allergeni completi ma apteni, ovvero piccole molecole che diventano antigeni completi grazie al legame con  con proteine “carrier”;  possono avere un effetto irritante e, penetrando attraverso l’epidermide raggiungono facilmente le APC inducendo la risposta T cellulare specifica.


Quali sono i sintomi della dermatite allergica da contatto?

La prima manifestazione della dermatite da contatto è l’arrossamento cutaneo accompagnato da prurito intenso localizzato nella sede di contatto con l’allergene;  successivamente compaiono delle vescicole che tendono a rompersi (fase essudativa) e a formare delle croste. Nei casi in cui il contatto con l’allergene continui, la cute diviene spessa e iperpigmentata (lichenificazione), con fissurazioni e desquamazione costantemente accompagnata da prurito di notevole intensità. Se l’allergene viene assorbita ed entra in circolo, le lesioni possono estendersi a distanza dal punto di primo contatto. La fase di sensibilizzazione può durare da 10 a 15 giorni di solito è asintomatica. 

Diagnosi

La sede iniziale della comparsa delle manifestazioni cutanee può aiutare nel risalire all’allergene implicato. I test epicutanei o patch test sono considerate l’indagine  più appropriata per la diagnosi delle dermatiti allergiche da contatto.


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Allergia: che cos’è e quali sono i sintomi

L'allergia è provocata da un un'abnorme attività del sistema immunitario nei confronti di antigeni (allergeni) naturali. L' allergia è molto diffusa, interessa circa una persona su quattro. La diagnosi dell' allergia si effettua tramite esami della pelle o del sangue. I sintomi principali dell'allergia sono Insufficienza respiratoria Prurito Orticaria Edema delle mucose Sintomatologia gastrointestinale (nausea, vomito e diarrea) Collasso cardiocircolatorio. L'allergia è fortemente influenzata da fattori genetici.L' allergie è caratterizzata da una risposta infiammatoria agli allergeni; locale o sistemica. L'allergia può essere dianosicata attraverso test cutanei o Prick Test prevedono una serie di piccole punture sulla pelle del paziente.Il  Prick test è il test più semplice ed economico per la diagnostica dell' allergia.

Che cos’è l’allergia? L’allergia è provocata da un un’abnorme attività del sistema immunitario nei confronti di antigeni (allergeni) naturali, solitamente glicoproteine, oppure molecole sintetiche (farmaci e altre sostanze chimiche di vario uso), innocui per i soggetti sani, a cui l’organismo viene esposto con diverse modalità: per inalazione, ingestione,  inoculazione, contatto cutaneo e/o mucoso. La sintomatologia … Leggi tutto

Allergia al lattice

L'allergia al lattice è una reazione IgE mediata alle proteine presenti nel lattice.Il lattice si trova in moltissimi oggetti, da quelli utilizzati in ambito sanitario a prodotti di uso comune: guanti, cateteri, ma anche maschere da sub, materassi, giocattoli, preservativi e tanto altro.L'allergia al lattice insorge per contatto diretto, per inalazione a seguito dell'utilizzo di guanti lubrificati con amido di mais.I sintomi principali dell'allergia al lattice sono Asma bronchiale. Difficoltà respiratorie Rinocongiuntivite Tosse secca Edema della laringe Dispnea Orticaria  Gonfiore di labbra, lingua, palpebre, Arrossamento cutaneo, Prurito  Congiuntivite shock anafilattico La diagnosi di allergia ala lattice si avvale sia dei test  in vivo a lettura immediata (prick test), sia della ricerca IgE specifiche.Non esiste una cura per l'allergia al lattice.I farmaci antistaminici e corticosteroidipossono alleviare i sintomi dell''allergia ala lattice

Che cos’è l’allergia al lattice? Il lattice grezzo contiene principalmente acqua (60%), particelle di gomma (33% ) proteine idrosolubili (2%)  molte delle quali sono state riconosciute come allergeni. L’allergia al lattice insorge per contatto diretto, per inalazione (l’inalazione di proteine contenute nel lattice di gomma naturale), a seguito dell’utilizzo di guanti lubrificati con amido di … Leggi tutto

Orticaria: cause, sintomi,trattamento

 L’orticaria fa parte di un gruppo eterogeneo di malattie. Tutti i tipi e i sottotipi di orticaria sono caratterizzati da un comune caratteristico pattern che prevede lo sviluppo di lesioni cutanee orticarioidi e/o angioedema.  L’orticaria molto frequentemente è caratterizzata da pomfi, ossia chiazze eritemato-edematose rilevate fortemente puriginose e fugaci. L’angioedema è caratterizzato dalla comparsa improvvisa … Leggi tutto

Dermatite atopica

Malattie della pelle 

 La dermatite atopica è una malattia infiammatoria pruriginosa della cute a carattere cronico recidivante con esacerbazioni periodiche e presenta una maggiore prevalenza nei bambini atopici, cioè con predisposizione genetica allo sviluppo di malattie allergiche.   Epidemiologia   L’incidenza della dermatite atopica nell’età infantile è stimata intorno al 17% negli Stati Uniti con dati … Leggi tutto

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!CONTRO LA DERMATITE ATOPICA…FAI TRIS!

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